Positives

• One patient discovered they were copper deficient, with levels at 56 and Ceruloplasmin at 20. After two weeks of zinc and copper supplements, they felt “90% better” and regained their ability to live normally Reddit.
  
  
• In another report, a patient highlighted the importance of zinc and copper balance, noting that excessive zinc intake can lead to copper deficiency, which may cause “serious neurological and hematological problems” Reddit.
  
  

Negatives

• Patients given zinc (with or without vitamin C) in two large outpatient COVID cohorts saw no measurable benefit on symptom duration or severity, undermining the rationale for ratio supplementation in mild disease CIDRAP.
• Patients taking daily zinc since 2021 have developed copper deficiency myeloneuropathy with sensory loss, weakness and gait impairment, even when they believed they were balancing the ratio Neurology.

Hurdles & Side Effects

• A patient reported experiencing a wide range of symptoms for about three months before identifying and addressing their copper deficiency, highlighting the challenge of diagnosing and treating mineral imbalances Reddit.