Reviews

Summary

Positives

  • A patient reported dramatically improved sleep and resolution of debilitating sleep paralysis after switching from high-sodium Xyrem, with 79% of switchers preferring Xywav Drugs.com.

  • A patient appreciated the 92% lower sodium load due to blood pressure concerns and reported better cataplexy control on Xywav JCSM.

Negatives

  • A patient reported about 15 lbs of weight gain and increased hunger after switching to Xywav Drugs.com.

  • Patients described transient headache, nausea, and red eyes during the titration phase PMC.

Hurdles & Side Effects

  • Setting an alarm to take a second middle-of-the-night dose disrupts the very sleep the drug is meant to consolidate Mayo Clinic Connect.

  • REMS enrollment, central pharmacy shipping, and Schedule III paperwork delay starts for many patients Drugs.com.

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