Positives

• A long-hauler’s neurologist discovered that COVID caused toxic B6 accumulation, giving a clear treatment path of stopping B6 sources and waiting for natural clearance Reddit.
  
  

Negatives

• A patient taking a B-complex for 9 months suddenly crashed with extreme anxiety, body twitching, brain zaps, insomnia, and blurry vision from suspected B6 pyridoxine toxicity Reddit.
  
  
• A patient developed cervical dystonia, neuropathy, and Raynaud’s over 1.5 years from unknowing intake of 50mg+ B6 daily through a multivitamin and B-complex Reddit.
  
  

Hurdles & Side Effects

• A patient with high serum pyridoxine and no supplement intake explained that in Long COVID the cofactors needed to convert inactive B6 to active P5P are blocked, causing toxic accumulation even without supplementation Reddit.
  
  
• A commenter documented finding hidden B6 in melatonin supplements, fortified foods, energy drinks, and hydration powders, warning that exposure from unsuspected sources can prevent levels from dropping Reddit.