Positives

• A severe CFS patient (housebound) reports that 10 mg vinpocetine cleared brain fog and reduced nighttime awakenings from 5–10 per night down to 2–4 Reddit.
  
  

Negatives

• A user reports taking 10–30 mg vinpocetine daily for months with no noticeable effect whatsoever Reddit.
  
  

Hurdles & Side Effects

• The Department of Defense's Operation Supplement Safety reports that the FDA's tentative position is that vinpocetine does not meet the definition of a dietary ingredient, and that in 2019 FDA warned anyone pregnant or who may become pregnant to avoid the supplement entirely due to safety concerns. Opss.
• Drugs.com's vinpocetine monograph notes that the supplement affects platelet aggregation and clotting factors, so anyone on aspirin, an anticoagulant, or with low blood pressure (common in POTS-pattern Long COVID) should avoid it or use only with clinical supervision. Drugs.com.
• A Mayo Clinic Proceedings analysis of dietary supplement labeling found wide variability in actual vinpocetine content among commercial supplements, with some products containing little or none of the labeled dose, a brand-quality risk that ginkgo biloba shares but is somewhat better characterized. Mayoclinicproceedings.