Positives

• A patient who managed to obtain SIM01 directly from Hong Kong reported using it as part of their gut-microbiome recovery protocol, citing the published benefit profile (fatigue, memory, concentration, GI upset) as their reason for pursuing it Reddit.
  
  

Negatives

• Patients in the Long COVID community frustrated by SIM01’s limited availability have noted feeling “left out” given the documented benefits, with no equivalent commercial product available outside Hong Kong Reddit.
  
  

Hurdles & Side Effects

• SIM01 is only available from Hong Kong (CU Medicine spin-off) and does not ship to Europe; US patients have managed to import it via friends/relatives in Asia or proxy shipping services, with cost typically $80-150/month plus shipping Reddit.
  
  
• Patients trying to substitute domestic Bifidobacterium-based probiotics report mixed success; the specific 3-strain + 3-prebiotic combination in SIM01 hasn’t been replicated by any US-available product to date CU Medicine.