Positives

• One person with Long COVID found Selank to be “amazing for anxiety” and expressed a commitment to continue using this peptide due to its positive effects Reddit.
  
  
• One individual mentioned that Selank, commonly used as a nasal spray, helps significantly with anxiety, contributing to their overall symptom management Reddit.
  
  
• A patient working with a biomed and longevity expert included Selank in a “3-month peptide protocol” aimed at addressing mould issues and chronic inflammatory response syndrome (CIRS), Reddit.
  
  

Negatives

• Patients on Selank for anxiety and cognition commonly describe effects as real but modest, with patients expecting dramatic Long COVID brain fog clearance commonly disappointed Innerbody.
• Selank has no FDA approval and no placebo-controlled trials in healthy adults, so most US patients buy it from research-chemical vendors with no quality assurance, and lab testing has found a significant portion of online peptides are mislabeled, underdosed, or contain different compounds entirely Innerbody.
• The FDA has specifically warned about compounded Selank due to immunogenicity risk, where the body can mount a potentially life-threatening immune response — particularly concerning for already-immune-dysregulated Long COVID patients SafeHG.

Hurdles & Side Effects

• The cost of Selank and other peptides can be a significant barrier, with one patient reporting expenses of “roughly 700AUD per order”, requiring them to break up purchases due to financial constraints Reddit.