Positives

• One person with a chronic condition reported a significant improvement in energy levels, which they described as “tripled” after just six days of taking oxaloacetate Reddit.
  
  
• In another report, a patient, who had been bedridden due to Long COVID, found that oxaloacetate allowed them to resume activities like gym workouts and e-bike rides, significantly enhancing their “quality of life” Reddit.
  
  
• One patient noted that while oxaloacetate did not cure their condition, it helped their “Krebs Cycle to function more efficiently,” reducing reliance on glycolysis for energy Reddit.
  
  

Negatives

• Oxaloacetate CFS retails at roughly $499 for a 90-capsule bottle, putting full RESTORE-ME-style dosing in the $500-$600/month range; many ME/CFS patients describe the price as the deal-breaker even when symptoms might respond.
• Patients trying 100-500 mg doses for 6 weeks or more commonly report either no perceptible change in energy or only a tiny benefit that disappeared over time, prompting refund requests Health Rising.

Hurdles & Side Effects

• The cost of oxaloacetate can be a significant barrier, with one patient estimating a monthly expense of “$250” for their dosage, highlighting the financial burden of this treatment Reddit.