Positives

• One patient suggests that while vitamin B12 is well-known, vitamin E should also be considered due to its overlapping symptoms with B12 deficiency, particularly for muscles, nerves, and immune function Reddit.
  
  
• In a journey to manage POTS symptoms, a patient found that incorporating supplements, including Omega-3 and Vitamin E, contributed to a 70% improvement in their condition Reddit.
  
  
• In another report, a patient shared that after addressing various symptoms with a comprehensive supplement protocol, including Omega-3 and Vitamin E, they noticed significant improvement in their quality of life Reddit.
  
  

Negatives

• Drugs.com lists eructation (fishy burping), bad breath, heartburn, nausea and diarrhea as the most common omega-3 side effects, with patients often abandoning standard softgels because of the persistent fishy reflux Drugs.com.
• Many patients only get past the burps by switching to enteric-coated, lemon-flavored or frozen capsules — a trial-and-error workaround that adds cost and inconvenience without guaranteeing any symptomatic Long COVID benefit.

Hurdles & Side Effects

• One patient noted the financial burden of maintaining a supplement protocol, which included Omega-3 and Vitamin E, estimating it to cost “a few hundred bucks a month” Reddit.