Positives

• A long-hauler went from bedbound at 3% functioning to approximately 50–60% through Primal Trust and other neuroplasticity programs, using nervous system regulation and somatic practices without pushing through PEM Reddit.
  
  
• A Primal Trust member reported reducing fibromyalgia pain by 90% and discontinuing 11 years of medication through the somatic component of the program alone Reddit.
  
  

Negatives

• A patient reported being directly harmed by brain retraining, going from mild CFS to severe by blindly following a program’s instructions Reddit.
  
  

Hurdles & Side Effects

• Programs range from roughly $300 to $2,800, creating a significant cost barrier for patients who are not working, with some specifically seeking cheaper alternatives Reddit.
  
  
• Patients must already be competent at pacing and have spare energy to safely undertake a course; blindly following program instructions without proper pacing can trigger PEM and worsen their condition Reddit.