Positives

• One patient reported a "10-15% increase in baseline energy" after incorporating NAD+ IV infusions into their Long COVID treatment protocol, calling it a worthwhile boost Reddit.
  
  

Negatives

• One patient reported “I took this after hearing the reviews from the influencers... but I didn’t feel any different. No increase in energy” after their NAD+ IV session.
• Common side effects during the infusion include flushing, nausea, dizziness, and warmth caused by rapid niacin-flush conversion when NAD+ is pushed too quickly.

Hurdles & Side Effects

• One patient noted the complexity of managing mast cell activation syndrome (MCAS) alongside NAD+ therapy, especially because mast cells release substances like histamine and cytokines that can complicate the response Reddit.