Positives

• Patients with autoimmune-flavored Long COVID and lupus-like overlap have used mycophenolate to induce remission of immune-mediated symptoms Rheumatology.org.
  
  
• A patient with autoimmune connective tissue overlap reported staying on mycophenolate for nearly a decade with stable disease control and improved kidney function WebMD.
  
  

Negatives

• A patient on the generic version reported severe diarrhea, complete incontinence, and altered mental state that forced them to stop the drug WebMD.
  
  
• Patients on mycophenolate showed reduced seroconversion after SARS-CoV-2 vaccination, leaving them more vulnerable to reinfection that could worsen Long COVID PMC.
  
  

Hurdles & Side Effects

• A patient reported the brand-name medication would have cost nearly $1,000 per month without insurance coverage, requiring co-pay assistance to remain affordable Healthline.
  
  
• Patients face higher long-term risk of lymphoma, skin cancer, and serious infection while on the drug, requiring frequent blood-count monitoring CellCept.com.