Positives

• A patient with cancer-related muscle wasting reported improved lean body mass on enobosarm in clinical trials Wikipedia.
  
  
• A patient described ostarine as the mildest SARM, with strength gains and minimal side effects at lower doses WebMD.
  
  

Negatives

• A patient reported headache, fatigue, anemia, nausea, back pain, and lowered HDL cholesterol while on ostarine Wikipedia.
  
  
• A patient on extended high doses developed reduced libido, erectile dysfunction, insomnia, and depression from suppressed testosterone WebMD.
  
  

Hurdles & Side Effects

• A patient noted that even with lean mass gains, ostarine failed to improve actual muscle strength in trials, blocking FDA approval Wikipedia.
  
  
• A patient was frustrated by the lack of human pharmacokinetic data, leaving illicit dosing largely guesswork US Pharmacist.