Positives

• In the largest hydrogen-sulfide SIBO patient registry, 73% of patients responded to a low-sulfur diet, the highest response rate of any common intervention tracked medRxiv.
  
  
• Patients on a short low-sulfur trial described being able to eat fruits they had avoided for years without bloating, urgency or pain Fay Nutrition.
  
  

Negatives

• Clinicians point out that despite widespread use, no controlled trials have shown long-term benefit of strict low-sulfate, low-sulfur eating Dr Ruscio.
  
  
• A patient who narrowed intake to chicken and rice felt awful with anything else, illustrating how restrictive the protocol becomes for some Fay Nutrition.
  
  

Hurdles & Side Effects

• Patients are warned the diet is not safe long-term and is best run for 4-6 weeks under a clinician to avoid nutrient gaps Nutrition Resolution.
  
  
• Anyone with a CBS variant or thiol sensitivity must navigate overlapping low-thiol food lists that exclude eggs, alliums, cruciferous vegetables and many proteins simultaneously Specialists in Gastroenterology.