Positives

• A patient in a phase 1 trial gained 1.2 kg of lean body mass on just 1 mg per day for 3 weeks without adverse safety signals PMC.
  
  
• A hip fracture patient gained 9.1% lean body mass at 2 mg/day in a phase 2 trial over 12 weeks Wikipedia.
  
  

Negatives

• A patient developed lethargy and persistent tiredness from week 5 onward and noticed scalp shedding similar to anabolic steroids WebMD.
  
  
• A patient saw their natural testosterone drop sharply and required a long PCT recovery USADA.
  
  

Hurdles & Side Effects

• A patient was warned about reports of liver damage, heart attack, and stroke linked to LGD-4033 use WebMD.
  
  
• A patient noted the only safety data covered ~3 weeks of supervised use, leaving any longer cycle effectively unstudied PMC.