Positives

• A POTS patient with hyperadrenergic symptoms reported that holy basil (tulsi) tea suppressed their adrenaline rushes and produced a calming effect, though they also noted feeling slightly panicky Reddit.
  
  

Negatives

• Holy basil can lower blood sugar enough to cause hypoglycemia in patients already taking diabetes medication — relevant for Long COVID patients on metformin or other glucose-lowering drugs WebMD.
• Men trying to conceive are commonly advised to avoid high-dose tulsi until human fertility data exists, because animal work showed 2 g of fresh tulsi lowered FSH and LH and reduced sperm count ResearchGate.

Hurdles & Side Effects

• Holy basil may interact with common Long COVID supplements including antihistamines (Pepcid), niacin, and vitamin C; patients taking multiple supplements should check for interactions before adding tulsi Reddit.