Positives

• In a clinical study, hexarelin raised left-ventricular ejection fraction in normal and GH-deficient participants, with the cardioprotective signal occurring independently of GH release PMC.
  
  
• A participant with GH deficiency described improved exercise tolerance after acute hexarelin infusion, with hormonal responses recorded alongside the cardiovascular effect Springer.
  
  

Negatives

• Users reported strong appetite spikes peaking 30 to 60 minutes after injection, plus mild bloating and tingling in the hands at higher doses Wikipedia.
  
  
• A patient on a longer cycle described joint aches, fluid retention, and rising fasting glucose consistent with sustained GH stimulation PMC.
  
  

Hurdles & Side Effects

• The cardioprotective evidence is largely from animal models and small early-phase human studies, leaving Long COVID patients without a validated clinical protocol PMC.
  
  
• No FDA-approved hexarelin product exists for any indication, so patients depend on compounding pharmacies or research-only suppliers and pay out of pocket Wikipedia.