Positives

• Telephone-delivered GMT for adults with mild traumatic brain injury improves rehabilitation accessibility for patients with multiple barriers to in-person care — relevant for Long COVID patients with PEM who can’t commute to a clinic PMC.
  
  
• GMT is most effective when combined with problem-solving therapy, personal goal setting, external cueing/prompting, and ecological daily-life training rather than office-based paper-and-pencil tasks PMC.
  
  

Negatives

• Long COVID patients in the NIH-funded RECOVER-NEURO cohort (n=378) on cognitive interventions for brain fog (computerized cognitive training, structured cognitive rehabilitation, and tDCS combined with training) saw no benefit over control over 10 weeks, despite each having previously shown benefit in MS and traumatic brain injury Health Rising.
• Interventions that try to “exercise” the brain may fail in Long COVID and ME/CFS because patients lack the underlying energy resources needed to carry out repetitive cognitive training tasks Health Rising.

Hurdles & Side Effects

• GMT is typically delivered by occupational therapists or neuropsychologists in 7-9 weekly sessions; insurance coverage varies widely (TBI/ABI rehab benefits may apply, but Long COVID-specific coverage is rare), and the GMT manual is published if patients want to do self-guided work between sessions Trials.