Positives

• 95% of patients rated Estring comfort as excellent or very good and 95% found it very easy to use over a 12-week trial PMC.
  
  
• Physician and patient global assessment of vaginal symptoms improved in 83% of women using the ring PMC.
  
  

Negatives

• Patients reported increased vaginal secretions as the most common side effect Cleveland Clinic.
  
  
• Femring is dosed for systemic absorption and carries the same hot-flash dose warnings as oral HRT Mayo Clinic.
  
  

Hurdles & Side Effects

• Self-insertion and repositioning of the ring every 90 days deters some patients FDA.
  
  
• A patient noted breast cancer history boxed warnings cause clinicians to hesitate prescribing Cleveland Clinic.