Positives

• Dupixent averages 6.9/10 across 116 atopic-dermatitis reviews on Drugs.com (59% positive), including a parent who reported their child reached complete clearance of eczema and asthma after 2 years on the drug, and an adult who said they were almost 80% clear within a week and 100% clear after 3 years of treatment for debilitating hives Drugs.com.
• For asthma maintenance the drug rates 7.3/10 across 66 Drugs.com reviews with 62% positive, and one patient from the original FDA trial said they were in their fourth year of use with no side effects and that the medication “changed their life” Drugs.com.

Negatives

• Conjunctivitis is the most common adverse reaction, with patients on Drugs.com reporting red, inflamed, itchy eyelids and constant tearing four to six months after starting; one reviewer said the drug helped initially but they developed flares around the mouth and worsening eyesight, leading them to quit after 6 months Drugs.com.
• Cost is a recurring complaint: one Drugs.com reviewer reported a copay of $29,000/year after exhausting the $13,000 copay-card limit, and the manufacturer list price runs roughly $3,993 per carton of 2 injections.

Hurdles & Side Effects

• Insurance coverage requires documentation of a labeled indication, so Long COVID patients without comorbid Type 2 inflammation generally cannot get the drug paid for Dupixent.