Positives

• A patient with fibromyalgia said taking 5 mg cyclobenzaprine in the early evening let her sleep better than she had in years and wake the next day feeling rested Drugs.com.
  
  
• A patient reported getting a far more restful sleep on cyclobenzaprine and being able to sleep through the night instead of waking every hour, with daytime fatigue improved as a result Drugs.com.
  
  

Negatives

• A subset of patients in the same dataset reported significant next-day grogginess and dry mouth even at low doses, and discontinued treatment because the daytime sedation was worse than the underlying sleep disturbance Drugs.com.
  
  

Hurdles & Side Effects

• Cyclobenzaprine is prescription-only, and the brand Flexeril has been discontinued, so patients receive generic; the average retail price is about $54 for 30x10mg tablets but a GoodRx coupon brings it to roughly $4.68 and a SingleCare coupon to $7.80.
• The 10mg dose is much more sedating than 5mg; on Drugs.com's hangover reviews patients say “10mg simply knocks me out and leaves me feeling completely hungover and drained the next day,” and another wrote that even taking it before bed left them groggy “all day” Drugs.com.