Positives

• One patient said a previous CT-contrast exposure unexpectedly eased severe Benadryl-triggered restless legs, but this is an unusual side note rather than a reason to seek contrast as treatment. Reddit.

Negatives

• Some patients describe CT contrast as a flare trigger, with restlessness, chest tightness, dizziness, anxiety, weakness, fatigue, or burning sensations worsening after the scan. Reddit.

Hurdles & Side Effects

• The practical concern is emergency planning: one patient felt ER staff were not prepared to manage a severe contrast reaction and had to advocate for treatment during the episode. Reddit.