Positives

• Patients with Long COVID-related chronic pain, fatigue, or inflammation have tried whole-body cryotherapy, with some reporting reduced pain levels and improved sleep in the days following sessions Cleveland Clinic.

Negatives

• Patients with severe Long COVID and post-exertional malaise warn that the cold-shock response can trigger symptom flares; some recommend starting with localized cold exposure (cold showers, ice packs) before attempting whole-body sessions Cleveland Clinic.

Hurdles & Side Effects

• Cryotherapy sessions typically cost $40-$80 each (membership packages may bring per-session cost down); not FDA-approved or insurance-covered. Sessions are short (2-3 minutes at -200°F to -240°F) and patients must remove jewelry and wear protective gloves/socks Cleveland Clinic.