Positives

• A long-hauler with shortness of breath, high heart rate, and PEM started colostrum powder plus LP299v probiotic and reported feeling much better within days, including being able to tolerate coffee which previously caused terrible reactions Reddit.
  
  

Negatives

• A long-hauler who tried 200g of colostrum powder reported noticing no changes, and another patient taking it most days similarly saw no major benefit for LC symptoms Reddit.
  
  

Hurdles & Side Effects

• A patient giving colostrum a second chance for histamine and MCAS issues reported that the first time caused a horrible reaction including diarrhea and weakness Reddit.
  
  
• Dairy-free colostrum options like Kroma brand are available but significantly more expensive than standard bovine colostrum, creating a cost barrier for patients who cannot tolerate dairy Reddit.