Reviews

Summary

Positives

  • In the ACME study, patients had a 59% reduction in migraine pain at 1 hour vs 30% with sham PMC.

  • In the larger TEAM trial, 25.5% of patients reported pain freedom at 2 hours after acute use Migraine Science Collaborative.

Negatives

  • A patient reported forehead tingling or paresthesia as the most common side effect during stimulation American Migraine Foundation.

  • Long COVID-specific headache evidence is absent; patients extrapolate from migraine data without LC-specific RCTs NeurologyLive.

Hurdles & Side Effects

  • Patients face out-of-pocket device cost (~$400) plus ongoing electrode replacement fees WebMD.

  • A patient noted the 20-minute daily preventive sessions can be hard to maintain during cognitive crashes Migraine Canada.

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