Positives

• A case series reported sustained cognitive improvement for over a decade in patients on the Bredesen precision-medicine protocol, an outcome not described with standard Alzheimer's drugs PMC.
  
  
• In one clinical practice, more than 90% of adherent patients stopped deteriorating and over 60% saw measurable cognitive gains Apollo Health.
  
  

Negatives

• A UCSF neurologist publicly warned that the Bredesen protocol is not proven to prevent or reverse Alzheimer's despite its high price tag UCSF.
  
  
• A documented patient case described enormous difficulty with the diet, especially as a long-time vegetarian who had to give up pasta and nightly wine Family Medicine.
  
  

Hurdles & Side Effects

• A patient enrolling in ReCODE pays roughly $1,399 for the assessment plus $75/month membership and around $945 for genetic and lab work, before supplements that can exceed $150/month Nurture Brain Health.
  
  
• The Alzheimer Society of Canada labels the protocol false hope, citing the lack of randomized controlled trials behind its claims Alzheimer Society of Canada.