Positives

• One patient noted that a combination including baclofen significantly improved their symptoms, allowing them to manage their condition more effectively Reddit.
  
  
• A patient with post-vaccine tremors reported that after using baclofen for a month, almost all of their tremors resolved, and they no longer needed the medication Mayo Clinic Connect.
  
  
• One person with long COVID experienced a noticeable reduction in tremors and muscle spasms, attributing this improvement to medication treatment including baclofen Mayo Clinic Connect.
  
  

Negatives

• One patient noted that baclofen was among several treatments that failed to improve their long COVID symptoms, contributing to their ongoing frustration Reddit.
  
  

Hurdles & Side Effects

• Baclofen requires a prescription, and Drugs.com lists drowsiness in up to 28% of users and muscle weakness as common side effects, which often interfere with driving and daily function Drugs.com.
• Sudden discontinuation can trigger severe withdrawal including hallucinations, seizures, fever, and worsening spasticity, so doses must be tapered slowly under medical supervision PMC.