Positives

• A moderate-severity ME/CFS patient reported significant improvement after starting atorvastatin at 80 mg daily, and a patient said a high-dose statin started in September 2019 brought her into remission from moderate ME/CFS Phoenix Rising.
  
  

Negatives

• One patient experienced a severe relapse of muscle problems within a few days of starting Lipitor, stopped the drug, restarted it later, and experienced a second relapse on re-exposure — the classic statin-associated myopathy pattern Phoenix Rising.
  
  

Hurdles & Side Effects

• Atorvastatin is one component of the Patterson/IncellDx Long COVID protocol (paired with maraviroc) and also appears in the Pretorius microclot protocol literature; forum members note that patients trying statins specifically for ME/CFS or Long COVID should be monitored for CK elevations and myopathy, not just lipid response Phoenix Rising.