Positives

• A randomized rat colitis study showed inner-leaf aloe extract had measurable anti-inflammatory, antioxidant, and healing-promoting effects on damaged intestinal mucosa Wiley.
  
  

Negatives

• WebMD reviewers report aloe vera supplements doing little for digestion, with one writing it did “absolutely nothing” and made stomach problems worse WebMD.
• Patients note that non-decolorized inner-leaf products still contain enough anthraquinone to trigger cramping and diarrhea, especially at the 4-8 oz daily doses some brands suggest WebMD.

Hurdles & Side Effects

• Lily of the Desert Inner Fillet 32 oz runs roughly $14.99-$15.99 and recommends 2 oz before meals up to 8 oz daily, which most users find tolerable but bulky to refrigerate after opening.
• Quality varies widely between decolorized inner-fillet and whole-leaf preparations, and the FDA does not monitor aloe supplements for purity, so patients are advised to choose IASC-certified bottles to avoid latex contamination NCCIH.