The Hoffman Centre for Integrative & Functional Medicine's website describes Dr. Bruce Hoffman's Calgary, Alberta practice (1133 17 Ave NW; 403-206-2333) as globally recognized for treating Mast Cell Activation Syndrome (MCAS), Mold Illness (CIRS), and Chronic Fatigue and Mitochondrial Disorders. The clinic uses Dr. Hoffman's proprietary 7 Stages to Health & Transformation framework — a roadmap for whole-person healing addressing physical, emotional, mental, and spiritual dimensions. Beyond complex chronic illness, the centre treats Lyme disease, autoimmune conditions, brain health (TBI, neurodegeneration), bioidentical hormone replacement, methylation defects, environmental toxicity (heavy metals, EMF), and IV chelation therapy. Patients are accepted from around the world; consultations require an initial intake.